Article
Effect of glutathione on aconitase in Escherichia coli.
Archives of biochemistry and biophysics - 15 Feb 1993
Gardner P R, Fridovich I
Abstract excerpt
The effect of glutathione (GSH) on the superoxide-sensitive [4Fe-4S]-containing aconitase of Escherichia coli was explored. A mutant deficient in GSH biosynthesis, designated gshA, grew slower in a defined medium than did the parental strain and this effect was more pronounced when succinate was supplied as the carbon source in place of glucose. This suggested that the citric acid cycle was compromised in the...
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