Article
Rapid, simple method for typing isolates of Mycobacterium tuberculosis by using the polymerase chain reaction
1 Feb 1993
Abstract excerpt
To develop a molecular typing method for Mycobacterium tuberculosis based on the polymerase chain reaction, oligonucleotide primers were designed to the ends of the insertion sequence IS6110 in an attempt to amplify DNA between clusters of this element on the genome. Although in many strains the copy number of this element is low and is distributed throughout the genome, most strains examined produced a banding...
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