Article
Proliferation of intracellular structures upon overexpression of the PMA2 ATPase in Saccharomyces cerevisiae.
The Journal of biological chemistry - 15 Sept 1993
Supply P, Wach A, Thinès-Sempoux D, Goffeau A
Abstract excerpt
The PMA2 gene is a presumed isogene of the PMA1 gene, encoding the major yeast plasma membrane H(+)-ATPase. When controlled by its own promoter, PMA2 in multiple copies does not complement a deficient PMA1 gene. Under the control of the PMA1 promoter, however, and expressed on a centromeric plasmid in yeast strains specially designed for stable expression, the PMA2 gene replaces the PMA1 gene to some extent,...
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