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Article

Simulation studies on ethanol metabolism in different human populations with a physiological pharmacokinetic model.

Journal of pharmaceutical sciences - 1 Jul 1993

Derr R F

Abstract excerpt

A physiological pharmacokinetic model of ethanol metabolism was used to simulate ethanol metabolism in standard, fasted, human males of the white American, white European, black American, and Japanese populations. Gastric ethanol metabolism accounted for only 0.24% of the dose in the several populations. In contrast, hepatic first-pass ethanol metabolism accounted for 3.7-4.2% of the dose. Ethanol elimination by...

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PMID: 8360839
DOI: 10.1002/jps.2600820702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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