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Article

Mutator plasmid in a nalidixic acid-resistant strain of Shigella dysenteriae type 1.

The Journal of antimicrobial chemotherapy - 1 Jun 1993

Ambler J E, Drabu Y J, Blakemore P H, Pinney R J

Abstract excerpt

A clinical isolate of Shigella dysenteriae from Kashmir, resistant to seven antibacterial agents including nalidixic acid, carried four plasmids, only one of which was transferable by conjugation. This plasmid, designated pYD1, conferred trimethoprim resistance and increased the frequency of mutation to nalidixic acid resistance in recipient strains. Thus, although nalidixic acid resistance was not carried on a...

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Identifiers

PMID: 8360123
DOI: 10.1093/jac/31.6.831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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