Article
Binding studies of RU486 in different Reuber hepatoma variants.
Receptor - 1 Jan 1993
Chasserot-Golaz S, Beck G
Abstract excerpt
The synthetic steroid RU486, which displays antiprogestin and antiglucocorticoid properties in different systems, inhibits cell growth in dexamethasone-sensitive H56 cells containing glucocorticoid receptors, as well as in dexamethasone-resistant S-H56-125 cells displaying a very low level of dexamethasone binding. In order to better understand the mechanism of the antiproliferative effect, the binding of RU486...
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