Article
Characterization of a temperature-sensitive mutant of Salmonella typhimurium defective in apolipoprotein N-acyltransferase.
The Journal of biological chemistry - 5 Aug 1993
Gupta S D, Gan K, Schmid M B, Wu H C
Abstract excerpt
On screening 440 temperature-sensitive (ts) mutants of Salmonella typhimurium, a mutant strain SE5312 which accumulated apolipoprotein (ALP) at 42 degrees C was identified. In vitro assay of apolipoprotein N-acyltransferase activity indicated that the mutant cell envelope contained reduced activi...
Topics
- Acylation
- Acyltransferases
- Alleles
- Amino Acid Sequence
- Animals
- Apolipoproteins
- Cloning, Molecular
- Copper
- Escherichia coli
- Genes, Bacterial
- Kinetics
- Lipoproteins
- Molecular Sequence Data
- Mutation
- Restriction Mapping
- Salmonella typhimurium
- Sequence Homology, Amino Acid
- Temperature