Article
[Current data on the pathogenesis of neurodegenerative diseases and some muscular disorders: therapeutic prospectives].
Orvosi hetilap - 1 Aug 1993
Vécsei L, Pál E
Abstract excerpt
Recent findings suggest that damaged mitochondrial DNA (mtDNA) may play a role in the development of Leber's hereditary optic neuropathy, Huntington's, Parkinson's and Alzheimer's disorders, as well as in that of encephalomyopathies. The mtDNA consist of 16,569 base pair and encodes 13 polypeptides, 2 ribosomal RNAs and 22 transfer RNAs. It is much more injurable than the nuclear DNA (nDNA) and since mtDNA...
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