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Oxidative Damage to RNA in Neurodegenerative Diseases

1 Jan 2006

Abstract excerpt

Since 1999, oxidative damage to RNA molecules has been described in several neurological diseases including Alzheimer's disease, Parkinson's disease, Down syndrome, dementia with Lewy bodies, prion disease, subacute sclerosing panencephalitis, and xeroderma pigmentosum. An early involvement of RNA oxidation of vulnerable neuronal population in the neurodegenerative diseases has been demonstrated, which is...

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PMID: 17047315
DOI: 10.1155/jbb/2006/82323

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