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Article

Additive, cooperative and anti-cooperative effects between identity nucleotides of a tRNA.

The EMBO journal - 1 Jul 1993

Pütz J, Puglisi J D, Florentz C, Giegé R

Abstract excerpt

We have investigated the functional relationship between nucleotides in yeast tRNAAsp that are important for aspartylation by yeast aspartyl-tRNA synthetase. Transcripts of tRNAAsp with two or more mutations at identity positions G73, G34, U35, C36 and base pair G10-U25 have been prepared and the steady-state kinetics of their aspartylation were measured. Multiple mutations affect the catalytic activities of the...

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Identifiers

PMID: 8335008
DOI: 10.1002/j.1460-2075.1993.tb05957.x
PMCID: PMC413550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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