A microsatellite marker within the duplicated D16S79 locus has a null allele; significance for linkage mapping.

doi:10.1159/000133570

Back to search

Article

A microsatellite marker within the duplicated D16S79 locus has a null allele; significance for linkage mapping.

Cytogenetics and cell genetics - 1 Jan 1993

Phillips H A, Thompson A D, Kozman H M, Sutherland G R, Mulley J C

Abstract excerpt

The dinucleotide repeat 16AC66f3 was characterised from D16S79A within a duplicated section of 16p13.11, which is duplicated on all normal chromosome 16's. This marker has a common null allele caused by polymorphism within one of the primer sites. A redesigned primer overcame this problem; howeve...

Topics

Alleles
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 16
Genetic Linkage
Genetic Markers
Humans
Molecular Sequence Data

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.