Normalization of affine gap costs used in optimal sequence alignment.

doi:10.1006/jtbi.1993.1054

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Article

Normalization of affine gap costs used in optimal sequence alignment.

Journal of theoretical biology - 21 Mar 1993

Allison L

Abstract excerpt

It is shown how to normalize the costs of an alignment algorithm that employs affine or linear gap costs. The normalized costs are interpreted as the -log probabilities of the instructions of a finite-state edit-machine. This gives an explicit model relating sequences that can be linked to proces...

Topics

Animals
Base Sequence
Biological Evolution
Computer Simulation
Models, Genetic
Models, Statistical
Molecular Sequence Data
Mutation
Probability
Sequence Alignment

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