Article
Transformation distances: a family of dissimilarity measures based on movements of segments.
Bioinformatics (Oxford, England) - 1 Mar 1999
Varré J S, Delahaye J P, Rivals E
Abstract excerpt
MOTIVATION: Evolution acts in several ways on DNA: either by mutating a base, or by inserting, deleting or copying a segment of the sequence (Ruddle, 1997; Russell, 1994; Li and Grauer, 1991). Classical alignment methods deal with point mutations (Waterman, 1995), genome-level mutations are studied using genome rearrangement distances (Bafna and Pevzner, 1993, 1995; Kececioglu and Sankoff, 1994; Kececioglu and...
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