Article
Does apolipoprotein(a) heterogeneity influence lipoprotein(a) effects on fibrinolysis?
Blood - 15 Jul 1993
Hervio L, Chapman M J, Thillet J, Loyau S, Anglés-Cano E
Abstract excerpt
High plasma levels of lipoprotein(a) [Lp(a)] are considered to be an independent risk factor for premature cardiovascular disease and are inversely associated with apolipoprotein(a) [apo(a)] isoform sizes. The contribution of apo(a) polymorphism to the inhibition of fibrinolysis, a mechanism that may favor thrombus development, was therefore evaluated by measuring the ability of Lp(a) particles of distinct apo(a)...
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