Article
[The molecular genetics of cystic fibrosis: the delta F508 allele in Mexican families].
Boletin medico del Hospital Infantil de Mexico - 1 Jun 1992
Rojas-Martínez A, Vázquez-Alemán R M, Gustincich S, Cantú J M, Barrera-Saldaña H A
Abstract excerpt
We have initiated the screening of the delta F508 cystic fibrosis (CF) mutation in our country basing our study on the polymerase chain reaction technique. In a sample of 10 western and a northeastern Mexican families that have at least one CF affected child, we found a delta F508 frequency of 59.1% among CF chromosomes. This frequency is similar to those reported for Spain. Furthermore, we found a correlation...
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