Article
Detection of the cystic fibrosis delta-F508 mutation at autopsy by site-directed mutagenesis.
American journal of medical genetics - 15 May 1993
Salcedo M, Chávez M, Ridaura C, Moreno M, Lezana J L, Orozco L
Abstract excerpt
In Caucasian populations cystic fibrosis (CF) is the most common autosomal recessive disorder. CF was previously considered rare in Mexico; however, the reported frequency is about 1% in autopsies. This discrepancy appears to be due to the inability to diagnose the illness during life. It is now...
Topics
- Autopsy
- Base Sequence
- Cystic Fibrosis
- DNA Mutational Analysis
- Humans
- Infant
- Liver
- Male
- Mexico
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Polymerase Chain Reaction