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Article

Transcriptional regulation of pituitary gonadotrophin subunit genes

1 May 1999

Abstract excerpt

The gonadotrophic hormones, LH and FSH, are synthesized in and secreted from gonadotroph cells in the anterior pituitary and comprise a common alpha-subunit and a hormone-specific beta-subunit. Gonadotrophic gene expression is activated during embryogenesis, independent of GnRH stimulation and increases as GnRH output increases, reaching adult levels at puberty. The transcriptional regulation of pituitary...

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Identifiers

PMID: 10357099
DOI: 10.1530/ror.0.0040117

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