Article
[Arrhythmias due to energy mosaic caused by gene mutations for energy transducing system in myocardium].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 1993
Ozawa T
Abstract excerpt
Recently, accumulation of oxygen damages and mutations in mitochondrial DNA during the life of an individual has been demonstrated to occur synergistically at a exponential rate. The mutations were caused by inherited germ line mutations and damage of mitochondrial DNA by active oxygen. Mitotic segregation of the mutated mitochondrial DNA causes energy mosaic among myofibire leading to arrhythmias. Two major...
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