Article
[Arrhythmias due to energy mosaic caused by gene mutations for energy transducing system in myocardium].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 1993
Ozawa T
Abstract excerpt
Recently, accumulation of oxygen damages and mutations in mitochondrial DNA during the life of an individual has been demonstrated to occur synergistically at a exponential rate. The mutations were caused by inherited germ line mutations and damage of mitochondrial DNA by active oxygen. Mitotic s...
Topics
- Arrhythmias, Cardiac
- DNA, Mitochondrial
- Energy Metabolism
- Gene Deletion
- Humans
- Mitochondria, Heart
- Mutation
- Point Mutation
