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Article

In serous ovarian neoplasms the frequency of Ki-ras mutations correlates with their malignant potential.

Virchows Archiv : an international journal of pathology - 1 Feb 1999

Haas C J, Diebold J, Hirschmann A, Rohrbach H, Löhrs U

Abstract excerpt

We analysed 44 tissue samples from serous ovarian neoplasms of different malignant potential for Ki-ras mutations by denaturing gradient gel electrophoresis (DGGE) and direct sequencing after microdissection. Point mutations at codon 12 were found in 7 of 20 tumours of low malignant potential (LMP) (35%) and in 2 of 6 well-differentiated carcinomas (33%). In contrast, no mutations were detected in the 11 poorly...

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Identifiers

PMID: 10071245
DOI: 10.1007/s004280050314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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