Article
Tandem-repeat internal mapping (TRIM) of the involucrin gene: repeat number and repeat-pattern polymorphism within a coding region in human populations.
American journal of human genetics - 1 Jul 1993
Urquhart A, Gill P
Abstract excerpt
We have analyzed the human involucrin gene in 41 British African-Caribbeans and 37 British white Caucasians by tandem-repeat internal mapping and DNA sequencing. A point mutation (i.e., Bc) in the last B repeat unit was found in 98.6% of British white Caucasians and in 52.4% of British African-Caribbeans. The distribution of repeat patterns was also different between the two populations. Nine previously...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Black People
- DNA
- Heterozygote
- Humans
- Molecular Sequence Data
- Point Mutation
- Polymorphism, Genetic
- Protein Precursors