Article
Recombinant human butyrylcholinesterase G390V, the fluoride-2 variant, expressed in Chinese hamster ovary cells, is a low affinity variant.
The Journal of biological chemistry - 5 Jul 1993
Masson P, Adkins S, Gouet P, Lockridge O
Abstract excerpt
Kinetics of recombinant fluoride-2 variant of human butyrylcholinesterase (Gly390 Val) secreted by Chinese hamster ovary cells were compared to recombinant usual and to usual butyrylcholinesterase purified from human plasma. The usual and fluoride-2 variant were indistinguishable with regard to h...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Butyrylcholinesterase
- CHO Cells
- Cloning, Molecular
- Codon
- Cricetinae
- Fluorides
- Genetic Variation
- Glycine
- Humans
- Hydrogen-Ion Concentration
- Kinetics
- Models, Molecular
- Models, Theoretical
- Molecular Sequence Data