Article
Human clusterin (CLI) maps to 8p21 in proximity to the lipoprotein lipase (LPL) gene.
Genomics - 1 May 1993
Fink T M, Zimmer M, Tschopp J, Etienne J, Jenne D E, Lichter P
Abstract excerpt
Clusterin (gene symbol: CLI) is a post-translationally nicked, two-chain plasma and tissue glycoprotein of 80 kDa. It forms high-density lipoprotein complexes with apolipoprotein A-I in plasma, functions as an inhibitor of the cytolytic reaction of the terminal complement proteins C5 to C9, and is secreted by Sertoli cells in large amounts into the seminal fluid. By isolating and characterizing three partially...
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