Article
Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus.
Diabetologia - 1 May 1993
Thorsby E, Rønningen K S
Abstract excerpt
Genes in the HLA complex are by far the most important in determining genetic predisposition or resistance to Type 1 (insulin-dependent) diabetes mellitus. In this review evidence is presented that the HLA genes mainly involved are those encoding some particular HLA-DQ molecules. Both among Black...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 6
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- Humans
- Immunity, Innate
- Major Histocompatibility Complex
