Article
Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus.
Diabetologia - 1 May 1993
Thorsby E, Rønningen K S
Abstract excerpt
Genes in the HLA complex are by far the most important in determining genetic predisposition or resistance to Type 1 (insulin-dependent) diabetes mellitus. In this review evidence is presented that the HLA genes mainly involved are those encoding some particular HLA-DQ molecules. Both among Black, Caucasian and Japanese subjects particular cis or trans encoded DQ molecules are significantly associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
