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Article

Reserpine-induced cell transformation without detectable genetic effects in Syrian hamster embryo cells in culture.

Carcinogenesis - 1 Jan 1994

Tsutsui T, Taguchi S, Hasegawa K, Ide T, Kojima K, Matsumura M, Huff J, Barrett J C

Abstract excerpt

Reserpine, a naturally occurring rauwolfia alkaloid, used mainly as an antihypertensive drug, was examined for its ability to induce cell transformation and genetic effects in Syrian hamster embryo (SHE) cells in culture. Treatment of SHE cells with 2 micrograms/ml of reserpine had no effect on cell growth, while 4 micrograms/ml of reserpine reduced the growth rate slightly and 8 micrograms/ml resulted in a...

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Identifiers

PMID: 8293535
DOI: 10.1093/carcin/15.1.11

Genes

SHE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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