Article
Abnormalities in premigratory granule cells in the weaver cerebellum defined by monoclonal antibody OZ42.
Anatomy and embryology - 1 Jan 1991
Smeyne R J, Pickford L B, Rouse R V, Napieralski J, Goldowitz D
Abstract excerpt
The immunoreactivity in OZ42, a neural cell specific antibody that recognizes premigratory cerebellar granule cells, was examined in early postnatal wild-type and weaver mouse cerebella. We find that the OZ42-positive staining in the external granular layer (EGL) is first seen at postnatal day 1 in the most posterior and ventral aspect of midline cerebellum in the wild-type and heterozygous weaver mouse. By...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Movement
- Cerebellum
- Embryonic and Fetal Development
- Female
- Genes
- Immunohistochemistry
- Male
- Mice
- Mice, Neurologic Mutants