Article
Ring Y chromosome: molecular characterization by DNA probes.
Cytogenetics and cell genetics - 1 Jan 1991
Pohlschmidt M, Rappold G, Krause M, Ahlert D, Hosenfeld D, Weissenbach J, Gal A
Abstract excerpt
A young male with a karyotype of 46,X,+ mar is described. Physical mapping of the marker chromosome by using Y-specific single-copy or moderately repeated DNA sequences as molecular probes showed that, in addition to the heterochromatic part of the Yq, a considerable portion of the euchromatin in both Yp and Yq had been lost. These findings suggest that the marker chromosome is a ring Y, for the generally...
Topics
- Adolescent
- Blotting, Southern
- Chromosome Mapping
- DNA Probes
- Female
- Humans
- Karyotyping
- Male
- Pedigree
- Phenotype
- Ring Chromosomes
- Sex Chromosome Aberrations