Article
Molecular characterization of tiny ring X chromosomes from females with functional X chromosome disomy and lack of cis X inactivation.
Genomics - 1 May 1995
Jani M M, Torchia B S, Pai G S, Migeon B R
Abstract excerpt
Small ring X chromosomes were first described in mosaic karyotypes of females with the relatively benign phenotype of Turner syndrome. The presence of these rings in association with more severe phenotypes including mental retardation has raised the possibility that they lack sequences necessary...
Topics
- Animals
- Base Sequence
- Dosage Compensation, Genetic
- Female
- Humans
- Hybrid Cells
- In Situ Hybridization, Fluorescence
- Intellectual Disability
- Male
- Mice
- Molecular Sequence Data
- Mosaicism