Article
Sequence diversity within the reovirus S2 gene: reovirus genes reassort in nature, and their termini are predicted to form a panhandle motif.
Journal of virology - 1 Feb 1994
Chapell J D, Goral M I, Rodgers S E, dePamphilis C W, Dermody T S
Abstract excerpt
To better understand genetic diversity within mammalian reoviruses, we determined S2 nucleotide and deduced sigma 2 amino acid sequences of nine reovirus strains and compared these sequences with those of prototype strains of the three reovirus serotypes. The S2 gene and sigma 2 protein are highl...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Genes, Viral
- Genetic Variation
- L Cells
- Mice
- Molecular Sequence Data
- Nucleic Acid Conformation
- Phylogeny
- RNA, Double-Stranded
- Recombination, Genetic
- Reoviridae
- Sequence Analysis, RNA