Article
Direct genetic selection for a specific RNA-protein interaction.
Nucleic acids research - 11 Dec 1993
MacWilliams M P, Celander D W, Gardner J F
Abstract excerpt
The decision between lytic and lysogenic development of temperate DNA bacteriophages is determined largely by transcriptional regulation through DNA-binding proteins. To determine whether a heterologous RNA-binding activity could control the developmental fate of a DNA bacteriophage, a derivative of P22 was constructed in which the chosen developmental pathway is regulated by an RNA-binding molecule interacting...
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