Article
Bacteriophage phi29 early protein p17 is conditionally required for the first rounds of viral DNA replication.
Gene - 26 Nov 1998
Crucitti P, Lázaro J M, Benes V, Salas M
Abstract excerpt
The gene 17 of the Bacillus subtilis phage phi29 is known to be involved in the viral DNA replication in vivo. In this paper, we show that the presence of protein p17 is required when phage infection occurs at a low multiplicity of infection (moi), which is probably the natural condition for infection, but is dispensable at a high moi. Gene 17 has been cloned in an Escherichia coli expression vector and protein...
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