Article
Safety evaluation of esperase.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Dec 1993
Hjortkjaer R K, Stavnsbjerg M, Pedersen P B, Heath J, Wilson J A, Marshall R R, Clements J
Abstract excerpt
Esperase is a proteolytic enzyme preparation that can be used as a processing aid in the food industry. The following studies were performed to establish safety for the consumer: oral toxicity study (13 wk) in the rat; teratogenicity study in the rat; gene mutation assays in Salmonella typhimurium and mammalian cells in vitro, and chromosome aberration assay in vitro. General toxicity was low; the effects seen...
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