Safety evaluation of esperase.

doi:10.1016/0278-6915(93)90010-v

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Article

Safety evaluation of esperase.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Dec 1993

Hjortkjaer R K, Stavnsbjerg M, Pedersen P B, Heath J, Wilson J A, Marshall R R, Clements J

Abstract excerpt

Esperase is a proteolytic enzyme preparation that can be used as a processing aid in the food industry. The following studies were performed to establish safety for the consumer: oral toxicity study (13 wk) in the rat; teratogenicity study in the rat; gene mutation assays in Salmonella typhimuriu...

Topics

Abnormalities, Drug-Induced
Administration, Oral
Animals
Cells, Cultured
Chromosome Aberrations
Dose-Response Relationship, Drug
Female
Food Handling
Gastric Mucosa
Humans
Hyperplasia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocytes

Male

Mutagenicity Tests

Mutation

Pregnancy

Rats

Rats, Sprague-Dawley

Source

Open in PubMed

Identifiers

PMID: 8282285
DOI: 10.1016/0278-6915(93)90010-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8282285-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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