Article
[Occupational exposure to isocyanates and individual susceptibility].
Sozial- und Praventivmedizin - 1 Jan 1993
Berode M, Savolainen H
Abstract excerpt
Patients with organic diisocyanate-induced pulmonary disease may be specially susceptible to the toxic effects of agent. Among 11 cases diagnosed in one year, the majority (10/11) were slow acetylators. The same patients were different from the control population in terms of alpha-1-antitrypsin phenotypes. Heterozygous combinations were more frequent than among controls. It seems that the combination of low...
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