[Occupational exposure to isocyanates and individual susceptibility].

doi:10.1007/BF01305362

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Article

[Occupational exposure to isocyanates and individual susceptibility].

Sozial- und Praventivmedizin - 1 Jan 1993

Berode M, Savolainen H

Abstract excerpt

Patients with organic diisocyanate-induced pulmonary disease may be specially susceptible to the toxic effects of agent. Among 11 cases diagnosed in one year, the majority (10/11) were slow acetylators. The same patients were different from the control population in terms of alpha-1-antitrypsin p...

Topics

Acetylation
Adult
Asthma
Biotransformation
Female
Genetic Predisposition to Disease
Heterozygote
Humans
Isocyanates
Male
Middle Aged
Pneumoconiosis
alpha 1-Antitrypsin

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