Article
Genetic susceptibility to fixed drug eruption: evidence for a link with HLA-B22.
Journal of the American Academy of Dermatology - 1 Jan 1994
Pellicano R, Ciavarella G, Lomuto M, Di Giorgio G
Abstract excerpt
BACKGROUND: Our observation of familial cases of fixed drug eruption (FDE) prompted us to consider a genetic predisposition to this disease. OBJECTIVE: Our purpose was to determine whether there is any association between FDE and any of the major histocompatibility complex class I or II alleles. METHODS: HLA class I and II typing was performed by lymphocytotoxicity assay in 36 unrelated patients with FDE....
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