Article
Synergistic interactions between two skeletal mutations in mice: individual and combined effects of the semidominants cleidocranial dysplasia (Ccd) and short digits (Dsh).
The Journal of heredity - 1 Jan 2000
Selby P B, Bolch S N, Mierzejewski V S, McKinley T W, Raymer G D
Abstract excerpt
Heterozygotes for cleidocranial dysplasia (Ccd) and short digits (Dsh) were crossed to test whether synergistic interactions occur between different dominant mutations whose individual pleiotropic phenotypic effects exhibit a common feature. These unlinked mutations are homozygous lethal, and the...
Topics
- Animals
- Cleidocranial Dysplasia
- Crosses, Genetic
- Female
- Genes, Dominant
- Genes, Lethal
- Heterozygote
- Homozygote
- Humans
- Male
- Mice
- Mice, Inbred C3H