Article
Recombinant cytokines as immunological adjuvants.
Immunology and cell biology - 1 Oct 1993
Nash A D, Lofthouse S A, Barcham G J, Jacobs H J, Ashman K, Meeusen E N, Brandon M R, Andrews A E
Abstract excerpt
This paper describes the bacterial expression and purification of bioactive recombinant ovine interleukin-2 (rovIL-2), interleukin-1 alpha (rovIL-1 alpha) and tumour necrosis factor alpha. These purified proteins had specific activities in appropriate bioassays of 1 x 10(7) 1 x 10(7) and 1 x 10(5...
Topics
- Adjuvants, Immunologic
- Animals
- Antibodies, Helminth
- Antigens, Helminth
- Cytokines
- Escherichia coli
- Haemonchiasis
- Haemonchus
- Interleukin-1
- Phenotype
- Protozoan Vaccines
- Recombinant Proteins