Article
Immunization with Babesia bigemina rhoptry-associated protein 1 induces a type 1 cytokine response.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Jan 1997
Ruef B J, Tuo W, Rodriguez S D, Roussel A J, Chitko-McKown C G, Palmer G H, McElwain T F, Canals A, Zarlenga D S, Gasbarre L C, Brown W C
Abstract excerpt
Rhoptry-associated protein-1 (RAP-1) homologues of Babesia bigemina and Babesia bovis are promising candidates for inclusion in subunit vaccines against these hemoprotozoan parasites. Partial protection against challenge infection has been achieved with native forms of these antigens, but the mec...
Topics
- Animals
- Antigens, Protozoan
- Cattle
- Cell Division
- Clone Cells
- Cytokines
- Female
- Immunization
- Interferon-gamma
- Interleukin-4
- Leukocytes, Mononuclear
- Lymph Nodes
- Phenotype
- Polymerase Chain Reaction