Article
Cross-sectional analysis of Met235-->Thr variant of angiotensinogen gene in severe, familial hypertension.
Biochemical and biophysical research communications - 15 Dec 1993
Bennett C L, Schrader A P, Morris B J
Abstract excerpt
A recent cross-sectional study of HTs in Salt Lake City and Paris has reported a significant association of a T704-->C (Met235-->Thr) variant in exon 2 of the angiotensinogen gene (AGT) with essential hypertension (HT). The present study used a new, direct PCR technique to detect this variant in 92 Caucasians with severe hypertension (HT) and two HT parents and 94 normotensive (NT) controls. Although frequency of...
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