Article
Analysis of Met235 to Thr variant of the angiotensinogen gene in relation to the blood pressure and family history of essential hypertension in Japanese children.
Acta paediatrica Japonica : Overseas edition - 1 Aug 1996
Kataoka S, Hashimoto N, Kakihara T, Tanaka A, Kawasaki T, Kikuchi T, Takahashi H, Uchiyama M
Abstract excerpt
A recent study reported a significant relationship between a T704-->C (Met235-->Thr) variant in exon 2 of the angiotensinogen gene in adults and essential hypertension. In the present study, this variant was detected in 131 Japanese children using a polymerase chain reaction. The allele frequency...
Topics
- Angiotensinogen
- Blood Pressure
- Child
- Female
- Gene Frequency
- Genetic Variation
- Humans
- Hypertension
- Japan
- Male
- Polymerase Chain Reaction
- Regression Analysis