Article
Analysis of Met235 to Thr variant of the angiotensinogen gene in relation to the blood pressure and family history of essential hypertension in Japanese children.
Acta paediatrica Japonica : Overseas edition - 1 Aug 1996
Kataoka S, Hashimoto N, Kakihara T, Tanaka A, Kawasaki T, Kikuchi T, Takahashi H, Uchiyama M
Abstract excerpt
A recent study reported a significant relationship between a T704-->C (Met235-->Thr) variant in exon 2 of the angiotensinogen gene in adults and essential hypertension. In the present study, this variant was detected in 131 Japanese children using a polymerase chain reaction. The allele frequency of the variant was 0.76. The genotype frequency of the homozygote for the allele was 0.59, and children who were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.