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Article

Alteration in cytoadherence and rosetting of Plasmodium falciparum-infected thalassemic red blood cells.

Blood - 15 Dec 1993

Udomsangpetch R, Sueblinvong T, Pattanapanyasat K, Dharmkrong-at A, Kittikalayawong A, Webster H K

Abstract excerpt

Hemoglobinopathies have a protective role in malaria that appears to be related to alterations in red blood cell (RBC) properties. Thalassemic RBCs infected with Plasmodium falciparum showed greatly reduced cytoadherence and rosetting properties as well as impaired growth and multiplication. A significant decrease in the levels of falciparum antigens associated with the membrane of infected beta-thalassemic RBCs...

Topics

Animals
Antibodies, Monoclonal
Cell Adhesion
Erythrocytes
Flow Cytometry
Genotype
Hemoglobins
Heterozygote
Humans
Plasmodium falciparum
Rosette Formation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

alpha-Thalassemia

beta-Thalassemia

Source

Identifiers

PMID: 8260712

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8260712-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Alteration in cytoadherence and rosetting of Plasmodium falciparum-infected thalassemic red blood cells.PMID 8260712Read ↗

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