Article
Analysis of the essential sequences of the factor VIII gene in twelve haemophilia A patients by single-stranded conformation polymorphism.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 1994
David D, Moreira I, Lalloz M R, Rosa H A, Schwaab R, Morais S, Diniz M J, de Deus G, Campos M, Lavinha J
Abstract excerpt
We report the analysis by single-stranded conformation polymorphism of the essential sequences of the factor VIII(FVIII) gene (total length about 14 kb) including the entire coding sequence, flanking intronic sequences and the putative regulatory sequences 5' to the gene, in twelve unselected hae...
Topics
- Base Sequence
- DNA, Single-Stranded
- Factor VIII
- Female
- Genetic Testing
- Hemophilia A
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Polymorphism, Genetic
- Portugal