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Article

Analysis of the essential sequences of the factor VIII gene in twelve haemophilia A patients by single-stranded conformation polymorphism.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 1994

David D, Moreira I, Lalloz M R, Rosa H A, Schwaab R, Morais S, Diniz M J, de Deus G, Campos M, Lavinha J

Abstract excerpt

We report the analysis by single-stranded conformation polymorphism of the essential sequences of the factor VIII(FVIII) gene (total length about 14 kb) including the entire coding sequence, flanking intronic sequences and the putative regulatory sequences 5' to the gene, in twelve unselected haemophilia A patients of Portuguese origin. Direct sequencing of the fragments with an altered migration pattern led to...

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Identifiers

PMID: 8054459
DOI: 10.1097/00001721-199404000-00016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of the essential sequences of the factor VIII gene in twelve haemophilia A patients by single-stranded conformation polymorphism.PMID 8054459Read ↗

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