Article
The binding of very low density lipoprotein remnants to the low density lipoprotein receptor in familial defective apolipoprotein B-100.
Atherosclerosis - 1 Aug 1993
Maher V M, Gallagher J J, Myant N B
Abstract excerpt
We have compared the affinity for low density lipoprotein (LDL) receptors of LDL and very low density lipoprotein (VLDL) remnants from patients with familial defective apo B-100 (FDB) with that of LDL and VLDL remnants from normal subjects. The binding affinity of FDB LDL was markedly reduced in...
Topics
- Adult
- Aged
- Apolipoprotein B-100
- Apolipoproteins B
- Binding, Competitive
- Cell Line
- Female
- Fibroblasts
- Heterozygote
- Humans
- Hypercholesterolemia
- Lipoproteins, LDL
- Lipoproteins, VLDL
