Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Production and characterization of VP4/VP7 reassortant swine rotaviruses derived from Gottfried and OSU parental strains.

American journal of veterinary research - 1 Oct 1993

Hesse R A, Couture L P, Ellsworth S R, Duhamel G E, Lu W, Dickinson E O, Benfield D A

Abstract excerpt

The ability of viral glycoproteins (VP) VP4/VP7 reassortant swine rotaviruses (RV) to induce cross-neutralizing antibody against parental serotypes was investigated in guinea pigs. Using selective culture conditions, we produced 10 reassortant viruses that contained gene segment 4 of the OSU RV strain and gene segment 9 of the Gottfried RV strain. These reassortant RV grew to high titer in cell culture and were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Viral
Share to Capsid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Capsid Proteins

Share to Cells, Cultured

Share to Genes, Viral

Share to Neutralization Tests

Share to Phenotype

Source

Identifiers

PMID: 8250387

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Production and characterization of VP4/VP7 reassortant swine rotaviruses derived from Gottfried and OSU parental strains.PMID 8250387Read ↗

Genotypic diversity of reassortants between simian rotavirus SA11 and human rotaviruses having different antigenic specificities and RNA patterns.Semantic proximity Read ↗

Structures of rotavirus reassortants demonstrate correlation of altered conformation of the VP4 spike and expression of unexpected VP4-associated phenotypes.Semantic proximity Read ↗

Preparation and characterization of a neutralizing monoclonal antibody directed to VP4 of rotavirus strain K8 which has unique VP4 neutralization epitopes.Semantic proximity Read ↗

Characterization of neutralization specificities of outer capsid spike protein VP4 of selected murine, lapine, and human rotavirus strains.Semantic proximity Read ↗

Immunodominance of the VP4 neutralization protein of rotavirus in protective natural infections of young children.Semantic proximity Read ↗

Generation of Recombinant Rotavirus with an Antigenic Mosaic of Cross-Reactive Neutralization Epitopes on VP4Semantic proximity Read ↗

Serotype-specific epitope(s) present on the VP8 subunit of rotavirus VP4 proteinSemantic proximity Read ↗

Analysis of gene selection in reassortant formation between canine rotavirus K9 and human rotaviruses with different antigenic specificities.Semantic proximity Read ↗

Interactions between the two surface proteins of rotavirus may alter the receptor-binding specificity of the virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.