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Article

Larger expansions of the CTG repeat in muscle compared to lymphocytes from patients with myotonic dystrophy.

Human molecular genetics - 1 Sept 1993

Anvret M, Ahlberg G, Grandell U, Hedberg B, Johnson K, Edström L

Abstract excerpt

The discovery that there is an expansion of a CTG repeat underlying myotonic dystrophy has led to new approaches in diagnosis and genetic counselling for this disorder. The size of the expansion correlates to a reasonable degree with the clinical symptoms within a given family. We report comparisons of the length of the expansion seen in lymphocytes and muscle samples from eight patients. In all cases the length...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Repetitive Sequences, Nucleic Acid

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Source

Identifiers

PMID: 8242063
DOI: 10.1093/hmg/2.9.1397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Larger expansions of the CTG repeat in muscle compared to lymphocytes from patients with myotonic dystrophy.PMID 8242063Read ↗

Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytesSemantic proximity Read ↗

Unstable DNA sequence in myotonic dystrophy.Semantic proximity Read ↗

Preliminary Findings on CTG Expansion Determination in Different Tissues from Patients with Myotonic Dystrophy Type 1.Semantic proximity Read ↗

Characterization of large CTG repeat expansions in myotonic dystrophy alleles using PCR.Semantic proximity Read ↗

Longitudinal increases in somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 are associated with variation in age-at-onset.Semantic proximity Read ↗

Size of the unstable CTG repeat sequence in relation to phenotype and parental transmission in myotonic dystrophy.Semantic proximity Read ↗

Decrease in the size of the myotonic dystrophy CTG repeat during transmission from parent to child: implications for genetic counselling and genetic anticipation.Semantic proximity Read ↗

Reduction in size of the myotonic dystrophy trinucleotide repeat mutation during transmission.Semantic proximity Read ↗

Myotonic dystrophy: correlation of clinical symptoms with the size of the CTG trinucleotide repeat.Semantic proximity Read ↗

The myotonic dystrophy gene.Semantic proximity Read ↗

Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients.Semantic proximity Read ↗

Molecular analysis for the myotonic dystrophy mutation in neuromuscular disorders.Semantic proximity Read ↗

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