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Article

Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes

1 Jan 1994

Abstract excerpt

The genetic basis of myotonic dystrophy is an unstable expansion of CTG repeats located in a gene on chromosome 19 that encodes a putative serine/threonine protein kinase. We studied the somatic mosaicism of the (CTG)n expansion in myotonic dystrophy patients. (CTG)n expansions were 2- to 13-fold greater in DNA isolated from skeletal muscle than in DNA from leukocytes in 10 of 11 patients with myotonic dystrophy....

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Identifiers

PMID: 8285579
DOI: 10.1002/ana.410350116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Unstable DNA sequence in myotonic dystrophy.Semantic proximity Read ↗

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