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Article

Characterization of large CTG repeat expansions in myotonic dystrophy alleles using PCR.

Human mutation - 1 Jan 1996

Cheng S, Barceló J M, Korneluk R G

Abstract excerpt

The CTG trinucleotide repeat expansions that are associated with myotonic dystrophy can be up to several thousand repeat units in length. We have developed a PCR protocol that has the potential to amplify mutant alleles with very large numbers of CTG repeats. The amplification uses the rTth DNA polymerase, XL system for long PCR targets together with primers which do not closely flank the repeat region and...

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Identifiers

PMID: 8723679
DOI: 10.1002/(SICI)1098-1004(1996)7:4<304::AID-HUMU3>3.0.CO;2-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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