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Article

Autosomal dominant hypoalphalipoproteinemia due to a completely defective apolipoprotein A-I gene.

Biochemical and biophysical research communications - 29 Oct 1993

Nakata K, Kobayashi K, Yanagi H, Shimakura Y, Tsuchiya S, Arinami T, Hamaguchi H

Abstract excerpt

Primary hypoalphalipoproteinemia is associated with atherosclerosis and exhibits significant familial aggregation. To reveal the presence of autosomal dominant hypoalphalipoproteinemia due to a completely defective apolipoprotein A-I gene, the apolipoprotein A-I gene was analyzed in a Japanese family with low levels of HDL cholesterol and apolipoprotein A-I. An insertion of a C in the region of the seven C run...

Topics

Adult
Amino Acid Sequence
Apolipoprotein A-I
Apolipoproteins
Arteriosclerosis
Base Sequence
Child
Female
Genes, Dominant
Genetic Carrier Screening
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hypolipoproteinemias

Molecular Sequence Data

Mutation

Oligonucleotide Probes

Reference Values

Source

Identifiers

PMID: 8240372
DOI: 10.1006/bbrc.1993.2341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8240372-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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