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Article

A maculopathy associated with the 15257 mitochondrial DNA mutation.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Nov 1993

Heher K L, Johns D R

Abstract excerpt

OBJECTIVE: To report a new retinal finding associated with the mitochondrial DNA mutation at nucleotide position 15257, a primary mutation associated with Leber's hereditary optic neuropathy. DESIGN AND PATIENTS: Clinical and historical data were collected for 24 visually symptomatic patients fro...

Topics

Adolescent
Child
DNA Mutational Analysis
DNA, Mitochondrial
Female
Fluorescein Angiography
Fundus Oculi
Humans
Macula Lutea
Male
Mutation
Polymerase Chain Reaction
Retinal Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Visual Acuity

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Identifiers

PMID: 8240104
DOI: 10.1001/archopht.1993.01090110061024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8240104-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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