Optic nerve sheath distention in Leber's optic neuropathy and the significance of the "Wallace mutation".

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Optic nerve sheath distention in Leber's optic neuropathy and the significance of the "Wallace mutation".

Journal of clinical neuro-ophthalmology - 1 Dec 1990

Smith J L, Tse D T, Byrne S F, Johns D R, Stone E M

Abstract excerpt

We recently encountered a 27-year-old man who presented an atypical clinical picture of Leber's hereditary optic neuropathy: His family history was negative, visual loss continued steadily for over 8 months, circumpapillary microangiopathy was equivocal, the optic discs showed large physiologic c...

Topics

Adult
DNA Mutational Analysis
DNA, Mitochondrial
Female
Fluorescein Angiography
Fundus Oculi
Humans
Magnetic Resonance Imaging
Male
Mutation
Myelin Sheath
Optic Atrophies, Hereditary
Optic Nerve
Tomography, X-Ray Computed

Source

Open in PubMed

Identifiers

PMID: 2150839

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2150839-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics