Accounting for bias in estimates of the rate of polygenic mutation.

doi:10.1098/rspb.1993.0116

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Article

Accounting for bias in estimates of the rate of polygenic mutation.

Proceedings. Biological sciences - 22 Sept 1993

Keightley P D, Mackay T F, Caballero A

Abstract excerpt

Experimental data on the rate of response to artificial selection in initially inbred lines or the rate of divergence among inbred sublines can be used to estimate the rate of increase in variance of quantitative traits from new mutations. So far estimates have been based on the infinitesimal mod...

Topics

Animals
Drosophila melanogaster
Mathematics
Models, Genetic
Mutation

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