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Article

Polygenic mutation in Drosophila melanogaster: estimates from response to selection of inbred strains.

Genetics - 1 Mar 1994

Mackay T F, Fry J D, Lyman R F, Nuzhdin S V

Abstract excerpt

Replicated divergent artificial selection for abdominal and sternopleural bristle number from a highly inbred strain of Drosophila melanogaster resulted in an average divergence after 125 generations of selection of 12.0 abdominal and 8.2 sternopleural bristles from the accumulation of new mutations affecting bristle number. Responses to selection were highly asymmetrical, with greater responses for low abdominal...

Topics

Animals
Biological Evolution
DNA Transposable Elements
Drosophila melanogaster
Female
Genes, Insect
Genetic Variation
Inbreeding
Male
Models, Genetic
Mutation
Selection, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Characteristics

Source

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Identifiers

PMID: 8005446
DOI: 10.1093/genetics/136.3.937
PMCID: PMC1205898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8005446-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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